Home - The YODA Project

Anyone, anywhere in the world should have free, unhindered access to not just my research, but to the research of every great and enquiring mind across the spectrum of human understanding.

Stephen Hawking

Our Mission

The Yale University Open Data Access (YODA) Project’s mission is to advocate for the responsible sharing of clinical research data, open science, and research transparency. The Project is committed to supporting research focused on improving the health of patients and informing science and public health. The YODA Project can only improve with your feedback. Please share your comments and ideas.

Our Model

The YODA Project seeks mutually beneficial partnerships with Data Partners, promoting independence, responsible conduct of research, good stewardship of data, and the generation of knowledge in the best interest of society. To participate, each Data Partner must transfer full jurisdiction over data access to the YODA Project.

How it works

Request Data

Are you ready to request data? To date, 459 trials have been identified as available. The YODA Project and Data Partners continue to identify and add more.

Get started

115 Publications!

Featured Articles

Articles making use of data shared through the YODA Project. Scroll through featured articles below or learn more about approved data requests.

*115 publications from 104 research projects.

View All Featured Articles.

Heterogeneity and Utility of Pharmaceutical Company Sharing of Individual-Participant Data Packages

Hopkins AM, Modi ND, Abuhelwa AY, Kichenadasse G, Kuderer NM, Lyman GH, Wiese MD, McKinnon RA, Rockhold FW, Mann A, Rowland A, Sorich MJ. Heterogeneity and Utility of Pharmaceutical Company Sharing of Individual-Participant Data Packages. JAMA Oncol. 2023 Dec 1;9(12):1621-1626. doi: 10.1001/jamaoncol.2023.3996. PMID: 37796495; PMCID: PMC10557028.
Association of proton pump inhibitor use with survival and adverse effects outcomes in patients with multiple myeloma: pooled analysis of three clinical trials

Almansour SA, Alqudah MAY, Abuhelwa Z, Al-Shamsi HO, Semreen MH, Bustanji Y, Soare NC, McKinnon RA, Sorich MJ, Hopkins AM, Abuhelwa AY. Association of proton pump inhibitor use with survival and adverse effects outcomes in patients with multiple myeloma: pooled analysis of three clinical trials. Sci Rep. 2024 Jan 5;14(1):591. doi: 10.1038/s41598-023-48640-1. PMID: 38182614; PMCID: PMC10770405.
Rapidly achieving clinical remission in ulcerative colitis indicates better endoscopic and histological outcomes

Chen R, Tie Y, Huang Y, Zhang X, Zeng Z, Chen M, Li L, Zhang S. Rapidly achieving clinical remission in ulcerative colitis indicates better endoscopic and histological outcomes. United European Gastroenterol J. 2023 Dec 30. doi: 10.1002/ueg2.12515. Epub ahead of print. PMID: 38159047.
Illusory generalizability of clinical prediction models

Chekroud AM, Hawrilenko M, Loho H, Bondar J, Gueorguieva R, Hasan A, Kambeitz J, Corlett PR, Koutsouleris N, Krumholz HM, Krystal JH, Paulus M. Illusory generalizability of clinical prediction models. Science. 2024 Jan 12;383(6679):164-167. doi: 10.1126/science.adg8538. Epub 2024 Jan 11. PMID: 38207039.
Combining Real-World and Randomized Control Trial Data Using Data-Adaptive

Harton J, Segal B, Mamtani R, Mitra N, Hubbard RA. Combining real-world and randomized control trial data using data-adaptive weighting via the on-trial score. Statistics in Biopharmaceutical Research. 2022;15(2):408–20. doi:10.1080/19466315.2022.2071982
Association between concomitant proton pump inhibitor use and survival of patients with metastatic prostate cancer receiving abiraterone acetate: a post-hoc analysis of pooled data from three randomized controlled trials

Fukuokaya W, Mori K, Yanagisawa T, Akazawa K, Shimomura T, Kimura T. Association between concomitant proton pump inhibitor use and survival of patients with metastatic prostate cancer receiving abiraterone acetate: a post-hoc analysis of pooled data from three randomized controlled trials. Prostate Cancer Prostatic Dis. 2023 Jul 18. doi: 10.1038/s41391-023-00695-x. Epub ahead of print. PMID: 37464102.
A powerful partnership: researchers and patients working together to develop a patient-facing summary of clinical trial outcome data

Ruzich E, Ritchie J, Ginchereau Sowell F, et al. A powerful partnership: researchers and patients working together to develop a patient-facing summary of clinical trial outcome data. Journal of the American Medical Informatics Association : JAMIA. 2023 Jun:ocad099. DOI: 10.1093/jamia/ocad099. PMID: 37341698.
Linkage of Young Mania Rating Scale to Clinical Global Impression Scale to Enhance Utility in Clinical Practice and Research Trials

Samara MT, Levine SZ, Leucht S. Linkage of Young Mania Rating Scale to Clinical Global Impression Scale to Enhance Utility in Clinical Practice and Research Trials. Pharmacopsychiatry. 2023 Jan;56(1):18-24. doi: 10.1055/a-1841-6672. Epub 2022 Jul 27. PMID: 35896419.
Ketamine for the treatment of major depression: a systematic review and meta-analysis

Nikolin S, Rodgers A, Schwaab A, Bahji A, Zarate C Jr, Vazquez G, Loo C. Ketamine for the treatment of major depression: a systematic review and meta-analysis. EClinicalMedicine. 2023 Aug 3;62:102127. doi: 10.1016/j.eclinm.2023.102127. PMID: 37593223; PMCID: PMC10430179.
Trajectory of fecal lactoferrin for predicting prognosis in ulcerative colitis

Chen R, Li L, Tie Y, Chen M, Zhang S. Trajectory of fecal lactoferrin for predicting prognosis in ulcerative colitis. Precis Clin Med. 2023 Sep 5;6(3):pbad022. doi: 10.1093/pcmedi/pbad022. PMID: 38025971; PMCID: PMC10680133.