Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events

Citation:

Wightman H, Butterly E, Wei L, McChrystal R, Sattar N, Adler A, Phillippo D, Dias S, Welton N, Clegg A, Witham M, Rockwood K, McAllister DA, Hanlon P. Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events. PLoS Med. 2025 Apr 7;22(4):e1004553. doi: 10.1371/journal.pmed.1004553. PMID: 40193407; PMCID: PMC12052138.