NCT02021292 – Prospective, Randomized, Placebo-controlled, Double-blind, Multicenter, Parallel-group, 24-week Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (MERIT-1) Posted on August 29, 2025 by Molly Willeford -
NCT00317486 – A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Tracleer (Bosentan) on Oxygen Saturation and Cardiac Hemodynamics in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology Posted on August 28, 2025 by Molly Willeford -
A double-blind, randomized, placebo-controlled study to assess the effect of Tracleer™ (bosentan) in combination with the initiation of epoprostenol therapy on cardiopulmonary hemodynamics in patients with severe pulmonary arterial hypertension Posted on August 28, 2025 by Molly Willeford -
NCT00367770 – A Multi-Center, Open-Label Extension Study to Protocol AC-052-405 to Evaluate the Safety and Efficacy of Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology Posted on August 28, 2025 by Molly Willeford -
NCT00706082 – A Two-stage Prospective Observational Cohort Study in Scleroderma Patients to Evaluate Screening Tests and the Incidence of Pulmonary Arterial Hypertension and Pulmonary Hypertension Posted on March 24, 2025 by Molly Willeford -
NCT03775421 – Prospective, Multi-center, Single-arm, Open-label Long-term Study Assessing the Safety, Tolerability, and Effectiveness of Macitentan in Fontan-palliated Adult and Adolescent Subject (RUBATO OL) Posted on January 21, 2025 by Molly Willeford -
NCT03153137 – Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Adult and Adolescent Subjects (RUBATO DB) Posted on January 21, 2025 by Molly Willeford -
NCT03359291 – A Single-center, Open-label, One-sequence, Two-treatment Study to Investigate the Effect of Macitentan at Steady State on the Pharmacokinetics of Rosuvastatin in Healthy Male Subjects. Posted on November 21, 2023 by Hollin Hakimian -
NCT02382016 – A Randomized, Double-blind, Placebo-controlled, Prospective, Multicenter, Parallel Group Study to Assess the Safety and Efficacy of Macitentan in Patients With Portopulmonary Hypertension Posted on August 5, 2023 by tsuperadmin -
NCT01474122 – Prospective, Randomized, Placebo-controlled, Double-blind, Multicenter, Parallel Group Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Patients With Ischemic Digital Ulcers Associated With Systemic Sclerosis Posted on December 4, 2020 by tsuperadmin -
The YODA Project