- CSR Summary CSR(s) for this product are publicly available on Health Canada’s website - https://clinical-information.canada.ca/search/ci-rc
- NCT02497287
- Primary Citation
- Data Specification Not Available
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Trial Information
Generic NameEsketamineProduct NameSPRAVATO®Therapeutic AreaBehaviors and Mental DisordersEnrollment802% Female63.4%% White85.7%
Product ClassNMDA receptor antagonistSponsor Protocol NumberESKETINTRD3004Data PartnerJohnson & JohnsonCondition StudiedDepressive Disorder, MajorMean/Median Age (Years)50.7
Supporting Documentation
- Collected Datasets Available
- Data Definition Specification Available
- Protocol with Amendments Available
- Statistical Analysis Plan Available
- Clinical Study Report Available
Approved Data Requests Associated with this Trial
- 2023-5149 : Sex Differences in the Antidepressant Effects of Ketamine
- 2021-4851 : Efficacy of esketamine for "treatment resistant depression" assessed by MADRS score after at least 4 weeks, an IPD meta-analysis
- 2021-4844 : Clinical predictors of antidepressant response to ketamine and esketamine: A systematic review and meta-analysis
- 2021-4637 : Data-sharing and re-analysis for main studies assessed by the European Medicines Agency - a cross-sectional study on EPARs
- 2019-3958 : Machine Learning for predicting treatment efficacy and clinical categorizations across mental health disorders.