Review by Joseph Ross – 05/01/2019 – 4:40pm

Data Request Number: 2019-3886 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

Would be useful for the investigators to clarify the utility of the data available via the YODA Project if IPD from other trials cannot be secured. Further, more detail would help peers understand whether the intention is to use different methods if only aggregate data can be secured and used for this study.

Recommendation for this data request: Approve