Review by Joseph Ross – 06/25/2018 – 4:58pm

Data Request Number: 2018-3236 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

This is a proposal for an interesting meta-analysis to examine whether azathioprine or anti-TNFa are more effective in the prevention of postoperative recurrence in Crohn’s Disease patients. Data from 1 study available via YODA Project, along with 5 additional studies for which the raw data have already been obtained, will be meta-analyzed. Just a note for the investigator that those other data sources will need to be uploaded to the YODA Project platform.

 Recommendation for this data request: Approve