Review by Joseph Ross – 07/24/2019 – 3:42pm

Data Request Number: 2019-3958 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

I suspect that there will not be many common data elements that can be used across the 107 studies, but the description of the work is clear and academic in focus. One issue that could be clarified is how machine learning models will be modified if certain data elements are available in some trials, but not others.

Recommendation for this data request: Approve