Review by Joseph Ross – 09/15/2021 – 5:55pm

Data Request Number: 2021-4779 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

Not for the public: This proposal looks very familiar to others we have approved, but I may be misremembering. Maybe other proposals did not examine placebo response … just flagging to be sure the investigators have seen them (and it’s a bit annoying that this is going to Vivli since 5 of the 7 studies are available through the YODA Project).

Recommendation for this data request: Approve