Review by Joseph Ross – 11/04/2016 – 1:16pm

Data Request Number: 2016-0960 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

Approve pending review by biostatistician. Also, one statement by requestors “We may also perturb the raw data from some RCTs to mimic non-RCT data to evaluate the model” should be clarified since requestors will not be able to modify the data provided in the secure environment.

Recommendation for this data request: Approve