Review by Nihar Desai – 03/10/2016 – 11:35am

Data Request Number: 2016-0766 Please use this space to provide any comments, feedback or concerns (optional):

The classification of gastrointerstinal disorders remains unclear. If the authors propose to look at different classes or antipsychotic drugs and GI disorders, I suspect they will be underpowered to make any meaningful observations.

Recommendation for this data request: Not Approve

would ask investigators to further develop the definitions, methods, and analysis plan.