Review by Nihar Desai – 07/21/2016 – 3:42pm

Data Request Number: 2016-1026 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Unsure, further clarification from requestor is needed Can the proposed research be reasonably addressed using the requested data?: Unsure, further clarification from requestor is needed Please use this space to provide any comments, feedback or concerns (optional):

1. What observational datasets are the authors going to use to “validate” these findings.
2. Why start with so many clinical conditions, why not use 1 as a “test case” like SGLT-2 inhibition. 

 Recommendation for this data request: Not Approve

Need further explanation as above.