Review by Nihar Desai – 08/30/2016 – 9:52am

Data Request Number: 2016-1026 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Unsure, further clarification from requestor is needed Please use this space to provide any comments, feedback or concerns (optional):

The proposal is essentially cut and paste from a PCORI grant submission. The authors propose applying this methodology to acute stroke and revasc strategies in chronic CAD but request trials of oral hypoglycemic agents. 

Recommendation for this data request: Not Approve

Need further clarification of clinical studies requested and the methods proposed.