Review by Nihar Desai – 11/27/2017 – 4:50pm

Data Request Number: 2017-2511 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

Does the study database include information on patient adherence?  If so, it would be advisable to conduct this analysis in an “on-treatment” cohort.

Recommendation for this data request: Approve