Review by Richard Lehman – 03/19/2020 – 11:45am

Data Request Number: 2020-4231 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

As a general principle, the value of a prognostic test depends on the clinical context and how it compares and combines with other prognostic makers, including clinical scores. Discussion of context and other clinical markers (e.g. BNP) would add to the value of this research.

Recommendation for this data request: Approve