The dissemination plan is vague and there are no references.
I think we need further detail on the number of other pediatric epilepsy trials being sought and the details of the proposed meta-analytic methods. Do the investigators have any experience of this kind of approach? It is important that they cite similar studies, and commit themselves to full publication of their methods and their eventual findings in a peer-reviewed journal.
If their approach is wholly novel then perhaps it should be set out for comment in a journal such as Trials or PLOS One, prior to the work being done.
see comments above.