Review by Richard Lehman – 11/06/2017 – 1:18pm

Data Request Number: 2017-2326 Is the scientific purpose of the research proposal clearly described?: Yes Will request create or materially enhance generalizable scientific and/or medical knowledge to inform science and public health?: Yes Can the proposed research be reasonably addressed using the requested data?: Yes, or it’s highly likely Please use this space to provide any comments, feedback or concerns (optional):

I applaud the intention of the proposed analysis, which is to help patients to understand the harms and benefits of each option for treating RA. However, this would depend on their personal objectives and weightings – in effect each person should constuct a personal PROM, which can be fluid rather than fixed over time. The idea of an aggregated G-PROM does not make sense to me. But I don’t feel that this opinion about their hypothesis should hinder our release of the data.

Recommendation for this data request: Approve