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Trial Information
Generic NameInfliximabProduct NameREMICADE®Therapeutic AreaDigestive System DiseasesEnrollment580% Female61.2%% White94%
Product ClassAntirheumatic Agents - Biologic Response ModifiersSponsor Protocol NumberC0168T21Data PartnerJohnson & JohnsonCondition StudiedCrohn's DiseaseMean/Median Age (Years)35
Supporting Documentation
- Collected Datasets Available
- Data Definition Specification Available
- Protocol with Amendments Available
- Statistical Analysis Plan Available
- Clinical Study Report Available
Approved Data Requests Associated with this Trial
- 2024-0656 : Development and Validation of a Graph Convolutional Neural Network Model for Predicting Treatment Response to Infliximab in Crohn's Disease Patients
- 2023-5212 : Influence of Race and Ethnicity on the Efficacy of Biologic Drugs for Inflammatory Bowel Disease
- 2022-5013 : Identification of the Need for Hematopoietic Stem Cell Transplantation in Crohn's Disease Patients: A Ma-chine Learning Approach
- 2022-4975 : Impact of concomitant baseline medication on efficacy of biologics and small molecules for Inflammatory Bowel Disease
- 2020-4341 : Estimating the association between TNF inhibitors and Legionnaires' disease and Listeriosis: A Meta-analysis
- 2019-4107 : Efficacy of biologic drugs in short-duration versus long-duration inflammatory bowel disease: individual-patient level meta-analysis
- 2019-4067 : Evidence-generation for biologics in pediatric studies
- 2018-3743 : The impact of biological interventions on health?related quality of life in adults with Crohn's disease
- 2018-3737 : Gender-based Differences in Response to Therapy in Inflammatory Bowel Disease
- 2018-3556 : Influence of Race and Ethnicity on the Efficacy of Biologic Drugs for Inflammatory Bowel Disease
- 2018-3476 : Efficacy of Crohn?s Disease Treatment Stratified by Disease Phenotype
- 2018-3131 : Treatment outcomes with biologics in moderate-severely active Crohn's disease stratified by ileal vs. colonic disease location
- 2018-3126 : Concomitant 5-ASA in Biologic-Treated Patients with Moderate-Severe Crohn?s Disease: A Post-Hoc Analysis of RCTs
- 2017-1856 : Impact of Age on Safety and Efficacy of Biologic Therapy for Inflammatory Bowel Disease
- 2017-1746 : Heterogeneity in relative treatment efficacy by age, sex, socioeconomic status and comorbidity
- 2016-1107 : The impact of anti-TNF drug levels on rates of fistula healing in individuals with Crohn?s Disease
- 2016-0919 : Comparative efficacy of biologics in resolving extraintestinal manifestations of IBD: a systematic review and meta-analysis
- 2016-0903 : Use of TNF antagonist therapies with or without steroids for induction in Crohn?s disease: A Meta-analysis
- 2015-0691 : Impact of Biologic Therapy on the Risk of Arterial and Venous Thromboembolic Events in Chronic Autoimmune Diseases: A Post-Hoc Analysis of RCTs
- 2015-0677 : Meta-analysis: Duration of inflammatory bowel disease and its impact on efficacy of biologic drugs
- 2015-0649 : Population Representativeness of Clinical Trial Study Samples
- 2015-0612 : Impact of Obesity on Disease Course and Response to Biologic Therapy in Inflammatory Bowel Disease: A Post-Hoc Analysis of RCTs
- 2015-0527 : Optimizing Infliximab in IBD: Developing a model to determine the optimal interval for monitoring infliximab concentrations
- 2015-0339 : Impact of the dose of immunomodulators on pharmacokinetics of biologics: Patient level meta-analysis of randomized controlled trials
- 2014-0334 : Gender Differences in Weight Gain in Patients with Inflammatory Bowel Disease Treated with Infliximab