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CSR Summary Not Yet Available
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NCT02489318
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Primary Citation
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Trial Information
Generic NameApalutamideProduct NameERLEADA®Therapeutic AreaAntineoplastic and Immunomodulating AgentsProduct ClassEndocrine TherapyPharmacological SubgroupHormone Antagonists and Related AgentsChemical SubgroupAnti-AndrogensCondition StudiedNeoplasms, Prostatic
Sponsor Protocol Number56021927PCR3002Enrollment1052Data PartnerJohnson & Johnson% FemaleN/AMean/Median Age (Years)68.4% White68.3%
Supporting Documentation
- Collected Datasets Available
- Data Definition Specification Available
- Protocol with Amendments Available
- Statistical Analysis Plan Available
- Clinical Study Report Available
Approved Data Requests Associated with this Trial
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- 2025-0268 : Detection of Subgroup Treatment Effects with Missing Patient-Reported Outcomes Data
- 2025-0188 : Deconstructing Patient-Reported Outcomes Using Bayesian Transition Models in Metastatic Prostate Cancer Receiving Androgen Receptor Pathway Inhibitors
- 2025-0172 : Leveraging Data Science Methods to Deliver Individualized Treatment Effects in Metastatic Hormone-Sensitive Prostate Cancer
- 2025-0136 : A novel risk stratification system of metastatic castration-sensitive prostate cancer using CHAARTED and LATITUDE criteria
- 2025-0044 : Machine Learning-Driven Identification of Clinical Subgroups with Heterogeneous Responses to Apalutamide in mCSPC
- 2024-0836 : Patterns of metastasis appearance and prognostic differences based on the type of metastasis in metastatic, castration-sensitive prostate cancer
- 2024-0784 : Investigating the Canonical Polycomb Repressive Complex 1 (cPRC1) as an Intrinsic Mechanism of Resistance to Apalutamide in Advanced Prostate Cancer
- 2024-0652 : IPD meta-analyses of the effects of ADT, docetaxel and androgen receptor pathway inhibitors for hormone-sensitive metastatic prostate cancer
- 2024-0584 : Initial ADT or ADT plus novel androgen receptor signaling inhibitors for patients with metastatic castration-sensitive prostate cancer
- 2024-0392 : Missing data considerations for patient reported outcome measures in randomized controlled trials
- 2024-0384 : Causal Mediation by PSA and pain in metastatic hormone sensitive prostate cancer: a pooled analysis of 5 randomized controlled trials
- 2024-0136 : Volume of bone metastasis and outcomes of apalutamide in patients with metastatic castration-sensitive prostate cancer
- 2023-5534 : Quality tolerance limit and duplicated patient investigation in clinical trials
- 2023-5274 : Statin use and outcomes in patients treated in the SPARTAN, TITAN and ACIS trial
- 2023-5242 : Patterns of disease progression in patients with metastatic, castration-sensitive prostate cancer
- 2023-5215 : Analysis of adverse events of prostate cancer drugs targeting on the hypothalamic pituitary gonadal axis
- 2023-5195 : Predictive modeling of adverse events and symptoms patterns in large scale clinical trials
- 2023-5187 : The association between antibiotics exposure and outcomes in men with prostate cancer
- 2023-5173 : Improving Outcome in Advanced Prostate Cancer: a Pooled Analysis of Randomized Controlled Trials